Multifunctional Top Drive Rapid Mixer Granulator (Single Pot) (THG Series)

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Engineered to eliminate cross-contamination through a top-drive design, addressing the most stringent pharmaceutical purity requirements and protecting operators from highly potent active ingredients.

Highly Active Pharmaceutical Ingredients (HPAPI): Safely processing compounds that require strict containment and contamination control.

Heat-Sensitive Materials: Utilizing low-temperature vacuum drying to preserve product integrity.

Advanced Granulation Processes: Fully capable of handling thermal melt granulation, effervescent tablet granulation, and complex crystallization processes.

Organic Solvent Processing: Perfectly suited for applications requiring closed-system handling and efficient solvent recovery.

ATTRIBUTES

  • Top-Driven Design: The transmission and sealing are located at the upper part of the equipment. This design ensures that the shaft seal does not directly contact the product, effectively preventing solvent/material penetration and eliminating “black spot” issues.
  • Integrated Multi-Process: Combines mixing, granulating, drying, and cone milling (wet/dry) into one unit.
  • High-Containment & Safety: Reaches containment levels up to OEB5, making it suitable for highly active and toxic material production.
  • Offers explosion-proof designs for organic solvents/dust, with an option for 12-bar explosion containment.
  • Efficient Drying: Utilizes vacuum + jacket heating + low-speed mixing + compressed air (nitrogen) purging to significantly improve drying efficiency and shorten processing time.

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Key Features & Benefits

Effective Volume Range:

From 75 L up to 1100 L, providing versatile options for different production scales.

Production Capacity:

15 kg to 440 kg per batch, catering to both pilot-scale and large-scale industrial requirements.

Mixing Impeller Rotation Speed:

Variable speed control from 4 – 180 RPM.

Granulating Chopper Rotation Speed:

Variable speed control from 300 – 3000 RPM.

TECHNICAL PARAMETERS

HD Series
SpecificationDetails
Effective volume 75 L - 1100 L
Total power 8.5 kW - 55.0 kW
Production Capacity15 kg - 440 kg
Mixing Impeller Rotation Speed4 - 180 RPM
Compressed air consumption0.4 - 1.8 m3/min
Compressed air pressure0.6 - 0.8 MPa

Product references: THG-10 / THG-25 / THG-50 / THG-100 / THG-150 / THG-200 / THG-300  MODELS

CONTACT US TODAY TO LEARN MORE

Ready to elevate your production capabilities? Contact Encap North America today to speak with one of our experts. We’ll provide you with all the information you need, including a personalized consultation to determine how our extensive range of machinery and equipment can meet your specific needs. Request a quote, schedule a virtual demo, or download our detailed product brochure to get started.

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